What is the ICD-10 code for primary hyperparathyroidism?

The ICD-10 code for primary hyperparathyroidism is E21.0, used when the condition is due to an overactive parathyroid gland.

How do you code secondary hyperparathyroidism due to CKD?

Use N25.81 for secondary hyperparathyroidism due to CKD, paired with the appropriate CKD stage code (N18.x).

ICD-10 Coding for Hyperparathyroidism(E21.0, E21.1, E21.3)

Save

Comprehensive guide on ICD-10 coding for hyperparathyroidism, including primary, secondary, and tertiary types. Learn about documentation requirements and coding pitfalls.

Also known as:

Parathyroid diseaseParathyroid disorder

Related ICD-10 Code Ranges

Complete code families applicable to Hyperparathyroidism

E00-E89Primary Range

Endocrine, nutritional and metabolic diseases

→

Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

Code	Description	When to Use	Key Documentation
E21.0	Primary hyperparathyroidism	Use when hyperparathyroidism is due to an overactive parathyroid gland, confirmed by lab and imaging results.	Elevated serum calcium (>10.5 mg/dL) Elevated PTH (>65 pg/mL) Imaging confirming parathyroid adenoma
E21.1	Secondary hyperparathyroidism, not elsewhere classified	Use when hyperparathyroidism is secondary to conditions like vitamin D deficiency.	Low 25-OH vitamin D (<20 ng/mL) Elevated PTH levels
N25.81	Secondary hyperparathyroidism of renal origin	Use when hyperparathyroidism is secondary to chronic kidney disease.	Elevated PTH with normal/low calcium eGFR <30

Primary ICD-10-CM Codes

Primary hyperparathyroidism

E21.0Billable

Differential Codes

Alternative codes to consider when ruling out similar conditions

Secondary hyperparathyroidism, not elsewhere classifiedE21.1

Primary hyperparathyroidismE21.0

Documentation & Coding Risks

Avoid these common issues when documenting Hyperparathyroidism.

Failing to document the cause of secondary hyperparathyroidism

Impact

Clinical: Misleading treatment plans, Regulatory: Non-compliance with coding standards, Financial: Potential claim denials

Mitigation

Always document underlying conditions, Use specific codes for causes

Using unspecified codes when specific types are documented

Impact

Reimbursement: May lead to reduced reimbursement rates, Compliance: Increases risk of audit failures, Data Quality: Decreases accuracy of health records

Mitigation

Always use specific codes like E21.0 or E21.1 when documentation supports it.

Unspecified coding

Impact

Using unspecified codes when specific documentation is available

Mitigation

Train staff to use specific codes based on documentation

Frequently Asked Questions

Documentation requirements, coding pitfalls and FAQs for conditions coded with E21.0.

Primary Code

E21.0

Primary hyperparathyroidism

Quick Navigation

ICD-10 codes5

Coding risks3

FAQs2

ICD-10 Coding for Hyperparathyroidism(E21.0, E21.1, E21.3)

Documentation & Coding Risks

Frequently Asked Questions

What is the ICD-10 code for primary hyperparathyroidism?

How do you code secondary hyperparathyroidism due to CKD?

Related condition guides