What is the ICD-10 code for prolactinoma?

The ICD-10 code for prolactinoma is D35.2, which denotes a benign neoplasm of the pituitary gland. If hyperprolactinemia is present, E22.1 should also be used.

When should E22.1 be used with D35.2?

E22.1 should be used with D35.2 when there is documented hyperprolactinemia associated with the prolactinoma.

ICD-10 Coding for Prolactinoma(D35.2, C75.1, E22.0)

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Comprehensive guide to ICD-10 coding for prolactinoma, including code relationships, documentation requirements, and clinical scenarios.

Also known as:

Pituitary adenomaHyperprolactinemia tumor

Related ICD-10 Code Ranges

Complete code families applicable to Prolactinoma

C00-D49Primary Range

Neoplasms

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Code Comparison: When to Use Each Code

Compare key differences between these codes to ensure accurate selection

Code	Description	When to Use	Key Documentation
D35.2	Benign neoplasm of pituitary gland	Use when a benign tumor of the pituitary gland is confirmed by imaging.	MRI or CT imaging confirming pituitary tumor Prolactin levels >200 µg/L
E22.1	Hyperprolactinemia	Use when elevated prolactin levels are documented and associated with a pituitary tumor.	Serum prolactin level >200 µg/L Symptoms of hormone excess such as galactorrhea

Primary ICD-10-CM Codes

Benign neoplasm of pituitary gland

D35.2Billable

Differential Codes

Alternative codes to consider when ruling out similar conditions

Malignant neoplasm of pituitary glandC75.1

Drug-induced hyperprolactinemiaE22.0

Documentation & Coding Risks

Avoid these common issues when documenting Prolactinoma.

Not documenting tumor size

Impact

Clinical: Inadequate assessment of tumor impact., Regulatory: Non-compliance with documentation standards., Financial: Potential for incorrect DRG assignment.

Mitigation

Use templates prompting for tumor size., Educate staff on documentation standards.

Using E22.1 alone for pituitary mass

Impact

Reimbursement: Incorrect coding may lead to denied claims., Compliance: Non-compliance with coding guidelines., Data Quality: Inaccurate clinical data representation.

Mitigation

Always pair E22.1 with D35.2 when a tumor is confirmed.

Incomplete documentation

Impact

Missing prolactin levels or imaging results.

Mitigation

Implement documentation checklists.

Frequently Asked Questions

Documentation requirements, coding pitfalls and FAQs for conditions coded with D35.2.

Primary Code

D35.2

Benign neoplasm of pituitary gland

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ICD-10 codes4

Coding risks3

FAQs2

ICD-10 Coding for Prolactinoma(D35.2, C75.1, E22.0)

Documentation & Coding Risks

Frequently Asked Questions

What is the ICD-10 code for prolactinoma?

When should E22.1 be used with D35.2?

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