E21 - Hyperparathyroidism and other disorders of parathyroid gland
ICD-10-CM Chapter 4: Endocrine, nutritional and metabolic diseases · E20-E35 Disorders of other endocrine glands (E20-E35) · Top-level category · FY2027
Coding Guidance
E21 is a non-billable heading. Report one of the 6 more specific codes below.
Includes, Excludes and Coding Notes
Mutually exclusive: these conditions are never reported together with this code.
- adult osteomalacia (M83.-)
- ectopic hyperparathyroidism (E34.2)
- hungry bone syndrome (E83.81)
- infantile and juvenile osteomalacia (E55.0)
Not part of this code; report both codes when the patient has both conditions.
- familial hypocalciuric hypercalcemia (E83.52)
Mutually exclusive: these conditions are never reported together with this code.
- galactorrhea (N64.3)
- gynecomastia (N62)
Mutually exclusive: these conditions are never reported together with this code.
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Instructional notes from the ICD-10-CM tabular list.
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
More Specific Codes (6)
Related condition guides
Documentation requirements, coding pitfalls and FAQs for conditions coded with E21.
More specific codes for E21
Codes at the same level as E21
- Congenital iodine-deficiency syndromeE00
- Iodine-deficiency related thyroid disorders and allied conditionsE01
- Subclinical iodine-deficiency hypothyroidismE02
- Other hypothyroidismE03
- Other nontoxic goiterE04
- Thyrotoxicosis [hyperthyroidism]E05
- ThyroiditisE06
- Other disorders of thyroidE07
- Diabetes mellitus due to underlying conditionE08
- Drug or chemical induced diabetes mellitusE09
- Type 1 diabetes mellitusE10
- Type 2 diabetes mellitusE11
- Other specified diabetes mellitusE13
- Nondiabetic hypoglycemic comaE15
- Other disorders of pancreatic internal secretionE16
- HypoparathyroidismE20
- Hyperfunction of pituitary glandE22
- Hypofunction and other disorders of the pituitary glandE23
- Cushing's syndromeE24
- Adrenogenital disordersE25
- HyperaldosteronismE26
- Other disorders of adrenal glandE27
- Ovarian dysfunctionE28
- Testicular dysfunctionE29
- Disorders of puberty, not elsewhere classifiedE30
- Polyglandular dysfunctionE31
- Diseases of thymusE32
- Other endocrine disordersE34
- Disorders of endocrine glands in diseases classified elsewhereE35
- Intraoperative complications of endocrine systemE36
- KwashiorkorE40
- Nutritional marasmusE41
- Marasmic kwashiorkorE42
- Unspecified severe protein-calorie malnutritionE43
- Protein-calorie malnutrition of moderate and mild degreeE44
- Retarded development following protein-calorie malnutritionE45
- Unspecified protein-calorie malnutritionE46
- Vitamin A deficiencyE50
- Thiamine deficiencyE51
- Niacin deficiency [pellagra]E52
32 more in this chapter.