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E88Non-billableSave

E88 - Other and unspecified metabolic disorders

ICD-10-CM Chapter 4: Endocrine, nutritional and metabolic diseases · E70-E88 Metabolic disorders (E70-E88) · Top-level category · FY2027

Coding Guidance

E88 is a non-billable heading. Report one of the 8 more specific codes below.

Includes, Excludes and Coding Notes

Excludes 1 — Not Coded HereFrom E88

Mutually exclusive: these conditions are never reported together with this code.

  • histiocytosis X (chronic) (C96.6)
Use Additional CodeFrom E88

Add a secondary code to identify the associated condition or cause when it is documented.

  • codes for associated conditions
Excludes 1 — Not Coded HereFrom E70-E88 Metabolic disorders (E70-E88)

Mutually exclusive: these conditions are never reported together with this code.

  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)
Excludes 2 — Not Included HereFrom E70-E88 Metabolic disorders (E70-E88)

Not part of this code; report both codes when the patient has both conditions.

  • Ehlers-Danlos syndromes (Q79.6-)
Excludes 1 — Not Coded HereFrom Chapter E00-E89

Mutually exclusive: these conditions are never reported together with this code.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
NotesFrom Chapter E00-E89

Instructional notes from the ICD-10-CM tabular list.

  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

More Specific Codes (8)

E88.0Disorders of plasma-protein metabolism, not elsewhere classified→E88.1Lipodystrophy, not elsewhere classified→E88.2Lipomatosis, not elsewhere classified→E88.3Tumor lysis syndrome→E88.4Mitochondrial metabolism disorders→E88.8Other specified metabolic disorders→E88.9Metabolic disorder, unspecified→E88.AWasting disease (syndrome) due to underlying condition→

Related condition guides

Documentation requirements, coding pitfalls and FAQs for conditions coded with E88.