D55Non-billableSave
D55 - Anemia due to enzyme disorders
ICD-10-CM Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism · D55-D59 Hemolytic anemias (D55-D59) · Top-level category · FY2027
Coding Guidance
D55 is a non-billable heading. Report one of the 6 more specific codes below.
Includes, Excludes and Coding Notes
Excludes 1 — Not Coded HereFrom D55
Mutually exclusive: these conditions are never reported together with this code.
- drug-induced enzyme deficiency anemia (D59.2)
Excludes 2 — Not Included HereFrom Chapter D50-D89
Not part of this code; report both codes when the patient has both conditions.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
More Specific Codes (6)
D55.0Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiencyBillable→D55.1Anemia due to other disorders of glutathione metabolismBillable→D55.2Anemia due to disorders of glycolytic enzymesCategory→D55.3Anemia due to disorders of nucleotide metabolismBillable→D55.8Other anemias due to enzyme disordersBillable→D55.9Anemia due to enzyme disorder, unspecifiedBillable→
Related condition guides
Documentation requirements, coding pitfalls and FAQs for conditions coded with D55.
Chapter Information
Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Range: D50-D89
View full chapterRelated ICD-10 Codes
More specific codes for D55
Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
D55.0›
Anemia due to other disorders of glutathione metabolismD55.1›
Anemia due to disorders of glycolytic enzymesD55.2›
Anemia due to disorders of nucleotide metabolismD55.3›
Other anemias due to enzyme disordersD55.8›
Anemia due to enzyme disorder, unspecifiedD55.9›
Other categories in this chapter
Codes at the same level as D55
- Iron deficiency anemiaD50
- Vitamin B12 deficiency anemiaD51
- Folate deficiency anemiaD52
- Other nutritional anemiasD53
- ThalassemiaD56
- Sickle-cell disordersD57
- Other hereditary hemolytic anemiasD58
- Acquired hemolytic anemiaD59
- Acquired pure red cell aplasia [erythroblastopenia]D60
- Other aplastic anemias and other bone marrow failure syndromesD61
- Acute posthemorrhagic anemiaD62
- Anemia in chronic diseases classified elsewhereD63
- Other anemiasD64
- Disseminated intravascular coagulation [defibrination syndrome]D65
- Hereditary factor VIII deficiencyD66
- Hereditary factor IX deficiencyD67
- Other coagulation defectsD68
- Purpura and other hemorrhagic conditionsD69
- NeutropeniaD70
- Functional disorders of polymorphonuclear neutrophilsD71
- Other disorders of white blood cellsD72
- Diseases of spleenD73
- MethemoglobinemiaD74
- Other and unspecified diseases of blood and blood-forming organsD75
- Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissueD76
- Other disorders of blood and blood-forming organs in diseases classified elsewhereD77
- Intraoperative and postprocedural complications of the spleenD78
- Immunodeficiency with predominantly antibody defectsD80
- Combined immunodeficienciesD81
- Immunodeficiency associated with other major defectsD82
- Common variable immunodeficiencyD83
- Other immunodeficienciesD84
- SarcoidosisD86
- Other disorders involving the immune mechanism, not elsewhere classifiedD89