D57Non-billableSave
D57 - Sickle-cell disorders
ICD-10-CM Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism · D55-D59 Hemolytic anemias (D55-D59) · Top-level category · FY2027
Coding Guidance
D57 is a non-billable heading. Report one of the 6 more specific codes below.
Includes, Excludes and Coding Notes
Excludes 1 — Not Coded HereFrom D57
Mutually exclusive: these conditions are never reported together with this code.
- other hemoglobinopathies (D58.-)
Use Additional CodeFrom D57
Add a secondary code to identify the associated condition or cause when it is documented.
- code for any associated fever (R50.81)
Excludes 2 — Not Included HereFrom Chapter D50-D89
Not part of this code; report both codes when the patient has both conditions.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
More Specific Codes (6)
Related condition guides
Documentation requirements, coding pitfalls and FAQs for conditions coded with D57.
Chapter Information
Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Range: D50-D89
View full chapterRelated ICD-10 Codes
More specific codes for D57
Other categories in this chapter
Codes at the same level as D57
- Iron deficiency anemiaD50
- Vitamin B12 deficiency anemiaD51
- Folate deficiency anemiaD52
- Other nutritional anemiasD53
- Anemia due to enzyme disordersD55
- ThalassemiaD56
- Other hereditary hemolytic anemiasD58
- Acquired hemolytic anemiaD59
- Acquired pure red cell aplasia [erythroblastopenia]D60
- Other aplastic anemias and other bone marrow failure syndromesD61
- Acute posthemorrhagic anemiaD62
- Anemia in chronic diseases classified elsewhereD63
- Other anemiasD64
- Disseminated intravascular coagulation [defibrination syndrome]D65
- Hereditary factor VIII deficiencyD66
- Hereditary factor IX deficiencyD67
- Other coagulation defectsD68
- Purpura and other hemorrhagic conditionsD69
- NeutropeniaD70
- Functional disorders of polymorphonuclear neutrophilsD71
- Other disorders of white blood cellsD72
- Diseases of spleenD73
- MethemoglobinemiaD74
- Other and unspecified diseases of blood and blood-forming organsD75
- Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissueD76
- Other disorders of blood and blood-forming organs in diseases classified elsewhereD77
- Intraoperative and postprocedural complications of the spleenD78
- Immunodeficiency with predominantly antibody defectsD80
- Combined immunodeficienciesD81
- Immunodeficiency associated with other major defectsD82
- Common variable immunodeficiencyD83
- Other immunodeficienciesD84
- SarcoidosisD86
- Other disorders involving the immune mechanism, not elsewhere classifiedD89