D57.453BillableSave
D57.453 - Sickle-cell thalassemia beta plus with cerebral vascular involvement
ICD-10-CM Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism · D55-D59 Hemolytic anemias (D55-D59) · Subcategory of D57.45 · FY2027
Applicable To
Inclusion terms listed under D57.453 in the ICD-10-CM tabular list.
- HbS-beta plus with cerebral vascular involvement
- Sickle-cell beta plus with cerebral vascular involvement
Includes, Excludes and Coding Notes
Code AlsoFrom D57.453
Report an additional code when both conditions apply.
- , if applicable cerebral infarction (I63.-)
Excludes 1 — Not Coded HereFrom D57
Mutually exclusive: these conditions are never reported together with this code.
- other hemoglobinopathies (D58.-)
Use Additional CodeFrom D57
Add a secondary code to identify the associated condition or cause when it is documented.
- code for any associated fever (R50.81)
Excludes 2 — Not Included HereFrom Chapter D50-D89
Not part of this code; report both codes when the patient has both conditions.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Related condition guides
Documentation requirements, coding pitfalls and FAQs for conditions coded with D57.453.
Chapter Information
Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Range: D50-D89
View full chapterOther codes in D57.45
Codes at the same level as D57.453
- Sickle-cell thalassemia beta plus with acute chest syndromeD57.451
- Sickle-cell thalassemia beta plus with splenic sequestrationD57.452
- Sickle-cell thalassemia beta plus with dactylitisD57.454
- Sickle-cell thalassemia beta plus with crisis with other specified complicationD57.458
- Sickle-cell thalassemia beta plus with crisis, unspecifiedD57.459